Generalized Epilepsy: Neurobiological Approaches
In: Springer eBook Collection
1 Historical Introduction -- I Clinical Background -- 2 The Syndromes of Generalized Epilepsy -- 3 Unanswered Clinical Questions in Generalized Epilepsy -- 4 The Relationship Between Sleep Spindles and Spike-and-Wave Bursts in Human Epilepsy -- II Fundamental Cellular and Neurotransmitter Mechanisms -- 5 Membrane Properties of Cat Betz Cells Studied In Vitro -- 6 Changes in Extracellular Ions Associated with Epileptiform Discharges -- 7 Role of Neurotransmitters in the Genesis of Epileptiform Discharges -- 8 Excitant Amino Acids in Epilepsy -- 9 Possible Epileptogenic Consequences of Misused GABAergic Relationships -- 10 Anticonvulsant Effects of Intracortical Chronic Infusion of GABA in Generalized Epilepsy -- 11 In Vitro Electrophysiology of a Genetic Model of Generalized Epilepsy -- III Thalamic and Cortical Mechanisms in Absence Attacks -- 12 Spindling, Incremental Thalamocortical Responses, and Spike-Wave Epilepsy -- 13 Physiology of Thalamic Relay Neurons: Properties of Calcium Currents Involved in Burst-Firing -- 14 Thalamo-Cortical Relationships in Generalized Epilepsy with Bilaterally Synchronous Spike-and-Wave Discharge -- 15 Focal and Generalized Epileptiform Activity in the Cortex: In Search of Differences in Synaptic Mechanisms, Ionic Movements, and Long-Lasting Changes in Neuronal Excitability -- 16 Pharmacology of the Inhibitory Systems in Primary Generalized Epilepsy of "Petit Mal" Type -- 17 Spontaneous Spike-and-Wave Discharges in Wistar Rats: A Model of Genetic Generalized Conconvulsive Epilepsy -- 18 Behavioral and Electrophysiological Studies of Absence Epilepsy -- IV Photosensitivity -- 19 Focal Discharges in Photosensitive Generalized Epilepsy -- 20 Photosensitive Epilepsy of the Baboon: A Generalized Epilepsy with a Motor Cortical Origin -- 21 Role of Dopamine in Generalized Photosensitive Epilepsy: Electroencephalographic and Biochemical Aspects -- 22 Inferences Regarding the Visual Precipitation of Seizures, Eye Strain, and Headaches -- V Generalized Convulsive Seizures -- 23 Animal Models of Generalized Convulsive Seizures: Some Neuroanatomical Differentiation of Seizure Types -- 24 Mechanisms Underlying Generalized Tonic-Clonic Seizures in the Rat: Functional Significance of Calcium Ions -- 25 Substantia Nigra-Mediated Control of Generalized Seizures -- 26 Mesencephalic Structures and Tonic-Clonic Generalized Seizures -- VI Metabolic and Neurochemical Studies -- 27 Metabolic Studies of Generalized Epilepsy -- 28 PET Studies of Generalized Epilepsy Induced by Convulsant Drugs Acting at the GABA-Benzodiazepine Receptor Complex -- 29 Postictal Compensatory Changes in Cortical Alpha-1 Receptors and Adrenergic-Mediated Phosphoinositol Metabolism Following Repeated Electroconvulsive Seizures in Rats -- VII Pharmacological Agents and Generalized Seizures -- 30 Cellular Actions of Petit Mal Anticonvulsants: Implication of Thalamic Low-Threshold Calcium Current in Generation of Spike-Wave Discharge -- 31 Mechanisms of Anticonvulsant Action of Valproate: An Overview and Perspective -- 32 Sedative Drug Withdrawal Seizures: Cellular Electrophysiological Mechanisms.